Search for: [Abstract = "The aim of this dissertation was to systematize information on pRCTs and the development of a tool for assessing the quality of trials without randomization. This information obtained by systematic reviews in medical databases \(PubMed, EmBase and Cochrane\). Pragmatic clinical trials have been shown to be a valuable and reliable source of information, and several tools have been provided for assessment their quality, including the PRECIS\-2. Critical evaluation of the questionnaires for quality assessment of observational studies was done. An own 19\-point questionnaire for assessing the quality of non\-randomized trials \(SQAROS\) was developed, in which attempts were made to answer the shortcomings of the found questionnaires. Using found\/developed scales, a model evaluation of olanzapine compared to aripiprazole effect in patients with schizophrenia experiencing agitation was performed. All presented results indicate that due to the utility of PRECIS\-2 and SQAROS \(which requires further validation\), the widespread use of such a tools is necessary for assessment of practical effectiveness."]

Number of results: 1