Search for: [Abstract = "The aim of the study was to find characteristic laboratory and\/or clinical features which distinguish APS patients with arterial thrombosis. We retrospectively studied 163 patients \(123 women and 40 men\) with APS. Patients were divided into 2 groups\: first 78 subjects with arterial thrombosis and second 85 subjects with other manifestations of APS. Patients were interviewed in a retrospective manner.Significant association between arterial thrombosis and the presence of aCL IgG \(p=0,036\; OR=2,032\) was found. The presence of LA showed no association with arterial events.There were no significant associations between any of the polymorphisms studied \(GP Ia\/IIa 807 C\/T, GP PIA1\/2 and Val\/Leu 247 β2GPI\) and arterial thrombosis in APS patients.We found a significant relationship with arterial thrombosis and livedo reticularis \(p=0,03\; OR=2,3\), especially in a stroke group \(OR=3,6\).In an univariate analysis of classic risk factors for atherosclerosis a predictors of arterial thrombosis were\: male sex \(p=0,03\; OR= 2,201\), hypercholesterolemia \(p<0,001\; OR=3,69\) and arterial hypertension \(p=0,002\; OR=2,81\). Multivariate analysis showed that independent risk factors for arterial thrombosis included arterial hypertension \(p=0,008\; OR=1,78\), hypercholesterolemia \(p=0,002\; OR=2,001\) and present smoking \(p=0,015\; OR=2,048\).In conclusion our results, point to an increased risk of arterial thrombosis in APS patients, who are male, show the presence of aCL IgG, suffer from arterial hypertension and\/or hypercholesterolemia and are present smokers."]

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