Search for: [Abstract = "The aim of the study was to evaluate\: the role of endothelial function in thepathogenesis of vasovagal syncope \(VVS\) using flow\-mediated dilation \(FMD\) andendothelium\-independent dilation \(EID\)\; the significance of FMD and EID aspredictive factors of VVS during head\-up tilt test \(HUTT\)\; the relationship betweenFMD and EID and the type of response to orthostatic stress according to VASIScriteria\; the usefulness of ultrasonographic parameters calculated from the pulsedDoppler velocity signal obtained during the study of FMD and EID\: maximumvelocity \(Vmax\), minimum velocity \(Vmin\), end\-diastolic velocity \(EDV\), timeaveraged maximum velocity \(TAMX\), pulsatility index \(PI\) and resistance index \(RI\)in diagnosis of reflex syncope. The study comprised 80 subjects\: gr. A\: 50 pts withVVS, aged 17\-39 yrs \(mean 26.6±7.5\), including 39 \(78%\) women and gr. K\: 30subjects without VVS, aged 17\-40 yrs \(mean 29.7±5.7\) including 23 \(76.7%\)women. Values of FMD and EID in pts with VVS were significantly greater thanthose in controls. It may point that the augmented endothelial function plays animportant role in VVS. The cut\-off points for FMD ≥ 10,49% and for EID ≥ 27.64%were predicting syncope occurrence during HUTT with sensitivity respectivly\: 100%and 64.6% and specificity\: 87.5% both for FMD and EID. Independent predictors ofVVS occurrence during HUTT were\: FMD, EDV during D2 phase of FMD and EI"]

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