Search for: [Abstract = "The aim of the study was to assess current frequency of all types of colon polyps potentially able to develop cancer \(adenomatous, hyperplastic or serrated\) as well as to determine polyp occurrence, its histological features and localization in relation to age and sex. We also tried to work out a total canceration potential index in relation to age, sex, number and histology of polyp carrying the risk of cancer development and foci of already developed cancer simultaneous with polyps. The study group consisted of 797 patients who between 2000 and 2006 was admitted to General and Oncologic Surgery Ward at the L. Rydygier's Provincial Specialist Hospital L. in Cracow to perform colonoscopy with polypectomy. Patients who underwent polypectomy constituted ca 10% of all patients with colonoscopies performed in this time in Surgery Ward at the L. Rydygier’s Hospital. In total, 1555 polyps \(1176 adenomatous polyps \(75.6%\), 291 hyperplastic polyps \(18.7%\) and 88 serrated polyps \(5.7%\)\) and 120 synchronous cancer foci were found in the studied population. All polyp’s type were significantly more frequent in men than in women. In men group the number of polyps increased in relation to age continuously, while in women polyps were most common in group 51\-70 years. The performed analysis has shown diversity in frequency of each type of polyp in colon segments \- adenomatous polyps were the most common in all segments, however, hyperplastic polyps were more frequent in rectum while serrated polyps were more common in proximal colon. Hyperplastic polyps had the lowest diameter while adenomas were the largest. Adenomatus polyps were more dysplastic than serrated polyps. The largest hyperplastic and serrated polyps were found in proximal colon, whereas the most dysplastic serrated polyps were observed in distal colon. The largest and the most dysplastic adenomatous polyps were found in distal colon, while villous or tubulovillous adenomatous polyps were more common in rectum. The patients with hyperplastic polyps were younger than patients with serrated and adenomatous polyps. Moreover, in cases of patients with hyperplastic polyps we found a difference in mean age between women and men \- the men were younger. Adenomatous and serrated polyps in patients of all ages and hyperplastic polyps in the youngest group \(up to 50 years of age\) were more often found in men than in women, while the frequency of hyperplastic polyps in the patients over 50 years of age was similar for both sexes. Adenomatous polyps characterized by disadvantageous histological structure \(large, high grade dysplasia, high villous content\) in the patients up to 50 years of age was more common in males, while in patients over 70 years of age \- in females. No significant structural differences in hyperplastic polyps between women and men were observed. The only difference in serrated polyps' structure concerned polyps' diameter in patients over 70 years of age \(with larger lesions in men\). In comparison to the older group, all polyps' types in patients up to 50 years of age were significantly more frequently found in rectum. The observation concerned both sexes equally. The topographic differences in polyp localization in relation to sex were found only in case of adenomatous and hyperplastic polyps in patients over 70 years of age. A relative shift of adenomatous polyps into distal part of the colon was observed in females, whereas hyperplastic polyps in the distal part of colon was more often found in males over 70 years old. Canceration potential index \(CPI\) values in all age groups were higher in males than in females. CPI values in male increased with age, while in female patients no statistically significant differences were observed. In patients over 50 years of age the largest part of total CPI was caused by rectal lesions, whereas in younger patients \- distal colon lesions."]

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