Search for: [Abstract = "T\]\), von Willebrand factor \(vWF\) antigen, vWF factor activity, VIII factor activity and troponin T were determined four times\: at rest, at peak exercise, one hour and 24 hours after exercise.Measurement of the peak thrombin generated was performed using calibrated automated thrombography using the assay by Hemker et al.. Measurement of CLT with the modified method by Lisman et al. was based on the assessment of lysis efficiency mediated by tissue plasminogen activator \(t\-PA\) after addition of tissue factor \(TF\) and phospholipids to plasma., Thirty\-two AS patients and 32 controls were included in the finalanalysis\; one subject from each group was excluded due to elevated blood white cell count and hypothyroidism respectively. Slightly lower hematocrit, hemoglobin, platelet count and more common hypercholesterolaemia were observed in AS patients, while other routine laboratory parameters were similar in both groups.The indices of the AS severity were\: peak aortic velocity \(Vmax\)=3.8±0.59 m\/s\; peak pressure gradient \(PPG\)=59.4±19.8 mmHg\; mean pressure gradient \(MPG\)=35.4±14.1 mmHg\; aortic valve area \(AVA\)=1.08±0.23 cm2\; AVA indexed to body surface area \(AVA\/BSA\)=0.58±0.1 cm2\/m2. Bicuspid aortic valves were found in 12 \(37.5%\) AS patients.The duration of stress test was shorter in AS group \(p=0.008\) and maximum workload was lower \(p=0.002\) and reached 81.3±21.1 W. During stress tes"]

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