Search for: [Abstract = "Syphilis is an infection caused by Treponema pallidum. Pregnancy has little effect on the clinical picture of syphilis, but syphilis infection can complicate pregnancy. Methods\: 24 patients with early syphilis, 14 of whom were pregnant, were included in the study. Blood was drawn for testing according to the study protocol. A single dose of penicillin was administered. Follow\-up was conducted until a normal serological response to treatment was achieved. Results\: The analyzed groups did not differ statistically significantly in the results of basic blood parameters. 6 months after the end of treatment, 42.9% of pregnant patients were characterized by an abnormal serologic response to treatment, at which time a normal serologic response was noted in all non\-pregnant patients. Pregnant women with syphilis were characterized by statistically significantly higher concentrations of cytokines typical of the regulatory response before and 6 months after the end. After treatment, concentrations of cytokines typical of regulatory response decreased significantly in both groups\; the older the pregnancy at the time of syphilis diagnosis, the statistically significantly longer time required to achieve a normal serological response to treatment. Conclusions\: Pregnant patients treated for syphilis during pregnancy are characterized by a slower serological response to tr"]

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