Search for: [Abstract = "Pregnancy complicated by T1DM requires a very precise monitoring of glycemic control. This target is difficult to reach with the currently used methods of glycemic control. HbA1c, a long\-term marker of glycemic control, does not reflect glycemic variability. Moreover, short\-term hyperglycemic episodes are frequently missed by a routine daily 8\-point glucose profile performed with glucose meters. Therefore, the currently used methods of glycemic assessment appear to be unreliable for the assessment of glycemic profiles in pregnancy complicated by T1DM and prevention of adverse outcomes. 1,5\-AG is a novel marker of short\-term glycemic control reflecting a period of the last 1\-2 weeks. It is currently used as a marker of acute hyperglycemia, including PPHG. However, it has been previously shown, that 1,5\-AG serum level depends on the renal glucose threshold which is decreased during pregnancy. Thus, 1,5\-AG utility as a marker of glycemia in this particular group of patients warrants new studies.This dissertation concerns the evaluation of the applicability of 1,5\-AG as a marker of glycemic control in pregnancy complicated by T1DM. The specific aims included\: to assess 1,5\-AG concentration in pregnant women with T1DM and physiological pregnancy, to analize the associations between 1,5\-AG and other methods of metabolic control, to evaluate 1,5\-AG discriminative accuracy in detecting"]

Number of results: 1