Search for: [Abstract = "PPHG, to search for the association between 1,5\-AG and neonate birth weight, and to evaluate 1,5\-AG as a biochemical predictor for LGA and macrosomia. \; There were 110 pregnant women with T1DM and 102 women in physiological pregnancy included into the study. Their serum 1,5\-AG was measured with an ELISA assay. In most women with T1DM 1,5\-AG level was measured in each trimester of pregnancy Subsequently, HbA1c level was assessed with HPLC. The data from SMBG and CGMS were analyzed for a 1 week period before blood collection for the laboratory measurements. In 85 women, birth weight data were collected. Characteristics involved clinical data concerning T1DM patients, pregnancy and newborns.Mean 1,5\-AG serum concentration in T1DM group was 4,5 μg\/ml which was threefold lower in comparison to physiological pregnancy. 1,5\-AG was a better predictor of mean and mean maximal glycemias as measured by glucose meters than HbA1c. Glycemic profiles were recorded with CGMS in 58 pregnancies. 1.5\-AG correlated significantly with the glycemic indices recorded by CGMS \- area under the curve at 140 mg\/dl, average maximal glucose and mean glucose while HbA1c correlated significantly only with mean glucose. Additionally, 1,5\-AG concentration remained the strongest predictor of AUC\-140 after adjusting in the multivariate model for HbA1c level, indices of SMBG and week of gestation. Birth weight wa"]

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