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Search for: [Abstract = "Objectives\: Arterial stiffness ia a risk factor of atherosclerosis and cardio\-vascular complications. Systemic lupus erythematosus \(SLE\) is an autoimmune disease in which patients’ prognosis depends contemporarily mainly on the progression of premature atherosclerosis. Aim\: To assess arterial stiffness in patients with coronary atherosclerosis \(CA\), cardiac syndrome X \(CSX\) and SLE, comparison the results with risk factors of atherosclerosis and with inflammatory markers, to determine the possible efficacy of atorvastatin on arterial stiffness in patients with SLE.Material and methods\: Patients with CSX \(n=44\), CA \(n=44\), SLE \(n=29\). SLE patients were randomized to atorvastatin group \(40 mg daily, n=14\) or placebo group \(n=15\). Levels of cholesterol, CRP, C3c and C4 were obtained. Pulse wave velocity \(PWV\) was measured\; patients with SLE were examined at baseline and after 1\-year follow\-up. Pulse wave analysis \(PWA\) was performed in CA and CSX group.Results\: CSX patients had lower PWV \(9,63±1,69 m\/s\) as compared to CA \(11,53±2,19 m\/s\) and higher as compared to CG \(8,07±1,03m\/s\). PWV in CSX and SLE \(8,87±2,1 m\/s\) were similar. PWV increased with age and blood pressure. Diabetes mellitus and smoking increased PWV only in CA group. Inflammatory markers didn’t influence PWV. After 1\-year follow\-up the tendency to PWV decrease was observed in atorvastatin group \(8,67±1,44 m\/s vs 7,8"]

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