Search for: [Abstract = "Nasal symptoms mostly acute, but often recurrent or chronic are the most common health problems in children. In the specifications of chronic non\-infectious rhinitis dominate inflammation of the nasal mucosa caused by allergic and non\-allergic factors. Studies on the clinical course of the allergic rhinitis \(AR\) are common, but in the case of non\-allergic rhinitis \(Non\-AR\) are rare, particularly in children.In view of the much similarity of the sings of AR and Non\-AR, the possibility of evolution of the inflammation processes, it would be advantageous to find the symptom\/s, marker\/s, which differentiate these two disorders and give prognostic factors.The aim of this study was to determine the interdependence between AR and Non\-AR by extracting the clinical symptoms, lung function parameters, biochemical and pathophysiological factors, differentiating these disorders in a group of school children with symptoms of non\-infectious rhinitis. Furthermore, the identification of such allergic inflammation markers which of that best discriminate AR and Non\-AR between each other.The study was cross\-sectional, comparative, done in Pulmonology and Allergy Clinic, Children's University Hospital in Cracow. There were 141children meeting the inclusion criteria for the study. In children enrolled to the study, it was done\: a questionnaire study, anterior rhinoscopy, determination of the exhaled nitric oxide level \(FeNO\), spirometry, nasal cytology, skin prick tests and blood collection for the determination of selected biochemical parameters \(serum total IgE \(tIgE\), complete peripheral blood eosinophilia \(Eoscomp\), interleukin\-4 \(IL\-4\) and tumor necrosis factor \(TNF\-\). Furthermore, evaluation of bronchial hyperresponsiveness \(BHR\) in children was made in exercise challenge tests by estimation of relative FEV1 fall \(%FEV1\). In the studied children, 45% were girls and 55% boys, in the age\: 10,62,2 and 10,52,1 years, respectively. AR and Non\-AR occurred with similar frequency in the studied children \(53% and 47%, respectively\) and the majority of rhinitis have a persistent form that 79% \(112\/141\), of which the persistent allergic rhinitis \(PAR\) \(n=63\) and persistent non\-allergic rhinitis \(PNon\-AR\) \(n=49\). Children with PNon\-AR were significantly younger than those with PAR \(mean difference app.1 year\) \(p=0,037\). Other demographic data \(gender,"]

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