Search for: [Abstract = "Materials and methodsA group of 88 male and female patients diagnosed with chronic periodontitis took part in the research. All the participants were thoroughly examined and had their ABI, mSBI indexes determined and PPD and CAL measured on the 1st day of the project, after 2 weeks and then after 6 weeks of treatment. The patients were divided into three groups at random.During the first visit each patient had a sample of GCF taken at the depth of> 5 mm from the pocket of a randomly chosen tooth. Moreover they had the level of IL\-8 determined by means of the ELISA test. Then the SRP procedure was applied to the patient's whole dentition.Subsequently, patients in each out of the three groups had a different material applied to the pocket of a chosen tooth. These were Chlosite \(CH\), Dentosept \(DE\), and 0,9% solution of sodium chloride \(KON\). After 2 weeks since the beginning of the treatment clinical examination and determination of the selected periodontal indexes was carried out in each patient.After 6 weeks each patient had the API and mSBI indexes determined and again a sample of GCF taken with the aim of testing the concentration of IL\-8 in it.ResultsIn all three groups of patients the levels of API and mSBI indexes decreased within the 6\-week period of treatment. The API index fell down from 62.8\(29.8\) on the first day to 35\(27.69\) after 6 weeks. The mSBI decreased from 56.6\(29.3\) to 27.5\(22.45\). The indexes were falling down gradually within the period of treatment. Statistical analysis proved positive correlation between these indexes. In most cases the depth of the pockets decreased to less than 3mm after 6 weeks of treatment. At the beginning of the project the PD value was 6.1 \(1.17\) and after 6 weeks of treatment it was equal to 3.9 \(1.15\). The results are statistically significant. The level of IL\-8 concentration decreased the most in patients whose pockets were deeper than 5mm and after the treatment were less than 3mm deep in all groups. The result is statistically significant. Moreover, a positive correlation was found between the depth of the pockets and the level of IL\-8 after 6 weeks of treatment in patients who had Chlosite and Dentosept applied. There was no connection found between the API, mSBI and CAL indexes and the level of IL\-8 in GCF in Chlosite and control groups of patients.However, there was a positive correlation between the API index and the level of IL\-8 in the group of patients treated with Dentosept after 6 weeks."]

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