Search for: [Abstract = "IntroductionCongenital heart defects \(CHD\) constitute second common cause of neonatal mortality despite general decrease of mortality rates during early life. Neonates with non\-diagnosed prenatally CHDs, which were delivered at lower reference hospitals, have worse chances due to the lack of immediate specialist care. This is particularly important regarding hospitals with remote locations from cardiosurgery\-cardiology centers. Prolonged hypoxia and metabolic acidosis during transportation are main causes of worse treatment outcomes in these cases. Prenatal diagnostics is extremely important. Diagnostic accuracy for detecting CHD at mid\-gestation in experienced hands reaches 88,7 to 99,0%. Among late first\-trimester ultrasound parameters related to CHD thickened nuchal translucency, abnormal ductus venosus \(DV\) flow, and tricuspid regurgitation should be considered. ObjectivesThe main aim of the study was the analysis of functional and structural cardiac abnormalities at the time of late first\-trimester scan between 11 and 14 weeks. MethodsFrom first\-trimester screening database records with known obstetric and neonatal outcomes were selected. Cases that demonstrated single pregnancies with fetal crown\-rump length between 45 and 84mm were enrolled to these studies. Only subjects examined by one of two experienced examiners certified in first\-trimester parameters and audited for more that 5 years by Fetal Medicine Foundation \(FMF\) were analyzed. The assessment of tricuspid and DV flow followed the FMF protocols. In study 1\- 1075 cases were analyzed, in study 2\- 5811, and in study 3\- 1084. In study 1 \(assessment of tricuspid flow\) and in study 2 \(evaluation of DV flow\) the following parameters were analyzed\: \-maternal age in subgroups of euploidy and aneuploidy\;"]

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