Search for: [Abstract = "Introduction The oral microbiota is the second most diverse and dynamic microbial ecosystem in the human body. It plays essential role in maintaining human health \[27\]. On the one hand, the imbalance of the oral microbiota \(referred to as dysbiosis\) may play a significant role in the pathogenesis of local and systemic disorders. On the other hand, such disorders can also affect the oral micriobiota. This work presents the assessment of the oral microbiota in two different disease states \- in patients treated in the Intensive Care Unit \(ICU\) due to SARS\-CoV\-2 infection and in patients with type 1 diabetes \(DM I\). Potential interactions between the SARS\-CoV\-2 virus and the human oral microbiota are not sufficiently understood \[15, 16\]. Patients with COVID\-19 requiring mechanical ventilation in an intensive care unit \(ICU\) are at high risk of developing severe systemic complications, including ventilator\-associated pneumonia, this maks its important to maintain and monitor oral health. Type 1 diabetes is a disease with different etiopathogenesis, clinical course, treatment and complications. Continuous subcutaneous insulin infusion \(CSII\) with personal insulin pump \(IP\) is a modern method of insulin administration, with evidence for its superiority to traditional multiple daily injections in metabolic control. A bidirectional relationship between or"]
