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Search for: [Abstract = "Introduction Patients who require continuous ventilator therapy or who have upper airway obstruction most frequently undergo tracheostomies, which involve opening the front wall of the trachea. Most frequently, a poly\(vinyl chloride\) tracheostomy tube is utilized to protect the airway. In the medical field, it is used to make items like drains, catheters, blood and infusion containers, endotracheal tubes, and tracheostomy tubes in a plasticized form PVC. This polymer is a crucial component of scientific research because of how widely it is used in healthcare settings. Functionalization of the polymer surface with drug nanoparticles is one of the intriguing study topics. It has been demonstrated that the use of antibiotic nanoparticles during the placement of orthopedic or maxillofacial surgery implants lowers the incidence of postoperative infection problems. One method for reducing systemic toxicity in local medication administration is the inclusion of nanoparticles into a polymer. Tracheostomy tubes receive less attention in the literature that details studies on medical devices. This opens up a new area for investigation, particularly with regard to functionalizing the polymeric material with antibiotic nanoparticles. When utilized in patients, biomaterial antibacterial qualities are crucial for minimizing local and systemic issues brought on by the growth of bacterial b"]

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