Search for: [Abstract = "Introduction Head and neck squamous cell carcinoma constitutes the sixth most common cancer in the world. Male to female incidence rates are greater than 2\: 1. The five year survival rate for patients with this disease has not improved appreciably since the early 1980s and remains at approximately 52%. A common problem occurring in cases of head and neck cancer is the recurrence of the disease either in the location of primary surgical resection \(although the surgical resection margins were histopathologically free of cancer cells\) or in a new place in upper respiratory tract. The risk of a local recurrence of the disease is stili high, estimated at about 10\-30%. Molecular biology achievements enabled to determine mechanisms responsible for tumor escape from host immunological surveillance, which are controlled by the regulation of apoptosis through the expression of various factors on cells surface. Tumor associated antigen RCAS1 \(receptor\-binding cancer antigen expressed on SiSo cells\) having gene at 8q23, is a type II membrane protein, expressed in various human cancer cells. It has been reported to be expressed with high frequency in breast, lung, larynx and pharynx, gallbladder, ovarian, uterine, bile duet cancer cells, in Reed Sternberg cells and erythroid progenitor cells. The RCAS1 protein acts as a ligand for a putative receptor present in various h"]
