Search for: [Abstract = "Introduction\: syncope is a temporary loss of consciousness, which is the result of global brain hypoperfusion, characterized by rapid onset, short duration, and spontaneous complete resolution.Aim of the study\:\- analysis of NT\-proBNP concentrations in patients with cardiogenic syncope compared to patients with neurogenic syncope.\- determination of the threshold values of NT\-proBNP to differentiate these groups of patients.\- assessment of the impact of serious arrhythmias on value of NT\-proBNP.Materials and methods\: we studied 100 patients with a history of syncope, in whom, according to ESC guidelines, the final diagnosis was neurogenic \(group I\) or cardiac syncope \(group II\).Results\: group I \- 50 patients \(31 F, 19 M\) with neurogenic syncope \(49 patients vasovagal syndrome\) and group II \- 50 patients \(25 F, 25 M\) with cardiogenic syncope \(47 of arrhythmias\).NT\-proBNP was significantly higher in group II in comparison to group I \(448.7 ± 212.2 vs. 68.2 ± 64.1, P <0.0001\)\; in the group with VT 526 ± 217 to 225 ± 230 pg \/ ml in patients without this arrhythmia \(p <0.0001\), with a third\-degree AV block 437 ± 205 compared to 259 ± 246 in those without the disorder \(p <0.001\).NT\-proBNP concentration at 210.5 pg \/ ml may predict cardiogenic cause of syncope with 98% specificity, 94% sensitivity and 94% negative predictive value.Conclusions\:\- the concentration of the peptide NT\-proBNP of 210.5 pg \/ ml demonstrated high sensitivity, specificity, and negative predictive value in determining the etiology of syncope.\- the concentration of peptide NT\-proBNP is higher in patients with syncope, in which there are structural disorders, in comparison to patients without these pathologies."]

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