Search for: [Abstract = "Introduction\: Somatostatin receptor scintigraphy \(SRS\) with use of labeled somatostatin analogs has important role in diagnosis\/therapy of neuroendocrine tumors \(GEP\-NET\). Because of its sensitivity and specificity SRS is the method of choice comparing to other USG,CT,MRI techniques. In SRS, receptor expression imaging is directly correlated with intensity of the radiopharmaceutical uptake. SRS is considered useful for clinical indications\: localization of primary tumor, evaluation of diseases extension. Evaluation of the uptake level in lesions is the significance indicator in therapy stratification with use of somatostatin analog labeled with 90Y or\/and 177Lu. The SPECT images reconstruction is crucial in interpretation of SRS. The choice of appropriate sets of OSEM Flash 3D™ algorithm \(subsets and iterations number for defined subsets number\) significantly influence on quality of reconstructed images and clinical assessment of target\/non\-target ratio \(TCS\/TCB\). There is still limited number of the publications which concern the optimization of iterative algorithms applied in reconstruction of SPECT images of GEP\-NET. Practically this subject was presented in the several experiments and the clinical trials referred to other diseases, mainly in aspect of comparison of FBP versus MLEM or\/and OSEM. The \[99mTc\-EDDA\/HYNIC\]octreotate improved the diagnostic eff"]

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