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Search for: [Abstract = "Introduction\: Initial, landmark studies on n\-3 polyunsaturated fatty acids \(n\-3 PUFAs\) confirmed their beneficial effects in the prevention of the cardiovascular diseases, especially in patients with coronary artery disease \(CAD\). However due to significant progress in treatment of cardiovascular diseases and assessment of n\-3 PUFA in variety of doses recent studies have been inconclusive. Objectives\: Assess the effect of n\-3 PUFA treatment at a dose of 2 g per day on endothelial function, selected coagulation parameters and platelet function in patients in patients with documented chronic coronary syndrome \(CCS\) and type 2 diabetes \(T2D\). Additionally, to assess the effect of the fatty acid composition of the serum phospholipid fraction on the clinical course of CAD. Methods\: To assess the effect of n\-3 PUFA on selected cardiovascular parameters patients were randomized in 1\:1 ratio into two groups\: 1\) optimal medical therapy \(OMT\) and n\-3 PUFA at the dose of 2 g per day— n\-3 PUFA group\; or 2\) placebo and OMT — placebo group\; and then treated for 3 months. The evaluation of the fatty acid composition of serum phospholipids was a case\-control comparison of patients with acute phase myocardial infarction \(AMI\) vs. CCS \(as a control group\). The fatty acid composition of the serum phospholipid was determined by gas chromatography. Results\: Despite significant increase in given"]

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