Search for: [Abstract = "Introduction\: Crohn’s disease is characterized by chronic and proceeding inflammation. In pediatric patients this chronic inflammatory condition may be associated with underweight, altered body composition \(protein deficiency\), which may lead to growth retardation, pubertal delay and decreased bone mineral density. The exclusive enteral nutrition \(EEN\), as a primary treatment in mild to moderate Crohn’s disease is highly effective in gaining clinical remission, has positive influence on inflammatory markers decrease and improves nutritional status. One of EEN claimed mechanism of anti\-inflammatory action is its impact on adipokines, produced by mesenteric fat tissue, which local periintestinal hypertrophy is diagnosed in patients with Crohn’s disease in medical imaging. Aim of the study\: Assessment of exclusive enteral nutrition remission induction treatment influence on nutritional status and body mass composition, estimated by bioimpedance analysis, and adipokines concentration in newly \- onset pediatric Crohn’s disease. Material and methods\: In years 2012 \- 2016 forty \- three patients hospitalized at the Department of Pediatrics, Gastroenterology and Nutrition, University Children’s Hospital, with newly \- onset, mild to moderate, uncomplicated Crohn’s disease, qualified to exclusive enteral nutrition remission induction treatment were enrolled into the study. 6 – week course of EEN was pursue by polymeric diet, administered by nasogastric tube or orally. Twenty two children, hospitalized at the Department of Pediatrics, Gastroenterology and Nutrition, University Children’s Hospital with no disorders served as controls. Bioimpedance analysis and adipokines concentration were estimated by enzyme – linked immunosorbent assay \(ELISA\) fourfold \(before diagnosis, after completion of the 6\- week exclusive enteral nutrition, at week 20 and at week 52\)."]

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