Search for: [Abstract = "Introduction\: Chronic periodontitis is an infective disease of tissue supporting the tooth. A decisive role in etiopathogenesis of this condition is played by microorganisms forming the bacterial biofilm.The presence of periodontal pathogens in the film leads to the activation of inflammatory processes which results in the production of cytokine IL \- 8 as a form of the body's immune response.The treatment of periodontitis consists in elimination of inflammatory mediators, modification of the response of a host, as well as regeneration of the periodontium tissue.The most important therapeutic procedures include scaling and root planning \(SRP\) together with local chemotherapy. The following antimicrobial agents were administered\: Chlosite produced by Ghimas and Dentosept produced by Phytopharm.Aim of the studyThe aim of the study is the assessment of clinical parameters and the level of IL\-8 concentration in the gingival crevicular fluid before and after the SRP procedure and after application of Chlosite, Dentosept and 0,9% solution of sodium chloride in patients with chronic periodontitis. \; Materials and methodsA group of 88 male and female patients diagnosed with chronic periodontitis took part in the research. All the participants were thoroughly examined and had their ABI, mSBI indexes determined and PPD and CAL measured on the 1st day of the project, after 2 weeks and then"]

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