Search for: [Abstract = "Inflammation is the defense response of tissues to damage. Acute inflammation can take a chronic form and result in many diseases. Research on inflammatory mediators has identified the anti\-inflammatory potential of polyunsaturated fatty acids \(PUFAs\) and their derivatives. Eicosapentaenoic acid \(EPA\) and docosahexaenoic acid \(DHA\) belong to the n\-3 PUFAs. They are precursors of anti\-inflammatory and pro\-resolving lipid mediators. Supplementation with EPA or DHA may reduce the risk of chronic inflammatory diseases. Changing the composition of the phospholipids, the organization of membrane microdomains, metabolism of lipids, and modifications of signaling pathways in pathological states are becoming new pharmacological targets. Adipose tissue is one of the leading centers of energy metabolism regulation. Fatty acid receptors play an essential role in glucose metabolism. They regulate both glucose uptake in adipose tissue by influencing the expression of GLUT\-4 glucose transporters, insulin receptor expression, and the adipogenesis process. Among others, adipogenesis disorders caused by inflammation in the adipose tissue led to insulin resistance, lipotoxicity, and steatosis. Factors influencing the development of obesity also include changes in the composition of the microflora, increased levels of lipopolysaccharide \(LPS\), leading to an increase in intestinal permeability and"]

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