Search for: [Abstract = "HD – UHDRS and CGI. Saccades were recorded using Saccadometer Advanced of Ober Consulting, and smooth pursuit, OKN and fixation using EOG of Hortman. For each ET patient and control subject neuropsychological tests for assessment of global cognitive functioning, memory, executive function, verbal fluency and tremor assessment by the use of accelerometer connected. The study shows that eye movement abnormalities are considerably more common in ET patients than in healthy subjects and their incidence in ET is similar to the other neurodegenerative disease like PD, SCA and HD. The most typical eye movement disturbances in ET are\: reflexive saccades dysmetria, smooth pursuit slowing as well as OKN slowing. In ET patient with concomitant cerebellar signs volitional saccades latency prolongation was additionally detected. The incidence of reflexive saccades dysmetria in ET increases with disease progression. Reflexive and volitional saccades latency relates to the executive dysfunction severity in ET patients."]
