Search for: [Abstract = "Group 1 included 71 children \(41 F and 30 M\) aged between 8.75 and 17.8 years \(x=13.8 ± 2.21\), Group 2 \- 62 subjects \(35 F and 27 M\) aged 7.42\-18.5 years \(x=14.2± 2.39\), and the controls \- 52 children \(27 F and 25 M\) aged 7.75\-17.6 years \(x=13.2± 2.93\). The diagnostic management included subjective and objective clinical assessment, EKG and chest X\-ray, transthoracic echocardiography, tilt test and 24\-hour EKG Holter monitoring. In the tilt test, the type of vasovagal reaction and the time of its occurrence were assessed. EKG Holter monitoring allowed for analyzing the following parameters of temporal and frequential HRV analysis\: 1. temporal domain\: standard deviation of normal RR intervals \(SDNN\), mean of the standard deviations of RR intervals for all 5\-minute segments of the entire recording \(SDNNI\), standard deviation of all 5\-minute mean normal RR intervals \(SDANN\), root mean square difference among successive RR normal intervals \(RMSSD\) and percentage of successive RR interval differences > 50 ms \(pNN50\),2. frequential domain\: low frequency \(LF\), high frequency \(HF\) and LF\/HF ratio. The results of TT and the values of HRV parameters were compared between Groups 1, 2 and 3. Groups 1 and 2 were additionally subdivided into subgroups with a positive and negative result of the tilt test \[TT\(\+\) and TT\(\-\)\]. In the thus formed subgroups, correlations were also performed between the reaction to TT and the investigated HRV parameters. p < 0.05 was accepted as denoting statistical significance. Results. Tilt test\: In Group 1 \(children with NS\), TT was positive in 41 \(58%\) and negative in 30 \(42%\) subjects. Vasovagal reaction of the MX type was the most commonly observed \(24 children\), while the VD reaction was less frequent \(15 children\) and the CI reaction was the least common \(2 patients\). In Group 2 \(children with MVP\), TT was positive in 18 \(28%\) and negative in 44 \(71%\) patients. Also in this group the MX type reaction was the most frequent \(12 children\), with VD being less common \(5 patients\), and CI showing the least prevalence \(1 child\). In Group 3 \(the controls\), TT was positive only in 2 children \(4%\), with one patient showing the MX type reaction and the other \- VD. The time till the onset of symptoms in TT\-positive children ranged from 7 to 57 min. \(x = 26.9 ±9.3 min.\), amounting, respectively, to 7\-54 min., \(x = 23 ±10.1 min. \- Group 1\), 7\-57 min, \(x = 26.5 ±14.1 min. \- Group 2\) and 28\-34 min., \(x = 31 ± 4.2 min. \- Group 3\). To assess sensitivity and specificity of the tilt test, the author compared TT results in children from Group 1 and 3, arriving at the following results\: sensitivity 58%, specificity 96%, positive predictive value 95%, and negative predictive value 63%. The TT results were also analyzed with respect to their dependence on age \(in three age groups\: <12 years, 12\-15 years and >15 years\) and gender. In children aged <12 years, the mixed type of reaction \(MX\) was noted in 4\/16 \(25%\) of Group 1 patients and in 2\/9 \(22%\) of Group 2 children, while the VD type was observed in 5\/16 \(31%\) of Group 1 patients and only in 1 children from the control group. In children in the 12\-15 year age group, MX was seen in 16\/33 \(48%\) of Group 1 patients and only in 6\/26 \(23%\) of Group 2 patients. The VD type was noted in 3\/33 \(9.1%\) of Group 1 patients and in 2\/26 \(7.7%\) of Group 2 patients."]

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