Search for: [Abstract = "Ghrelin is a hormone produced by neuroendocrine cells of gastric mucosa. Its concentration varies in cases of Helicobacter pylori \(Hp\) infection of stomach. However this relation is not completely defined. Determination of changes in ghrelin plasma and gastric mucosa concentrations in cases of diseases of gastric mucosa related to Hp infection constituted the aim of the study. 78 patients in whom endoscopy of upper gastrointestinal tract was performed in 2nd Chair of General Surgery of Jagiellonian University Medical College from January 2006 to May 2008 constituted material of the study. Patients were divided into four main groups on the basis of initial diagnosis made at admission to the Department. Group 1 – patients suffering from gastric cancer with concomitant Hp infection \(n=25\)\; Group 2 – patients with inflammatory lesions of prepyloric region with Hp infection and concomitant duodenal peptic ulcer disease \(n=18\)\; Group 3 – patients with atrophic gastritis of fundus and body of the stomach without Hp infection found during endoscopy \(n=10\)\; Group 4 – patients without morphological and histological lesions of gastric mucosa and without Hp infection \(n=25\). Ghrelin plasma concentration was measured in fasting plus 60 and 90 minutes after meal. In the group 1 measurement was performed twice – before and after the surgical operation. Furthermore gastrin and leptin co"]

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