Search for: [Abstract = "Gastroparesis is the severe neuromuscular dysfunction and is defined as delayed gastric emptying of solids in the absence of mechanical obstruction. Patients with this disorder may present dyspepsia symptoms as early satiety, upper abdominal discomfort, bloating, or nausea with or without vomiting. It can frequently result from longstanding diabetes mellitus and vagal nerve injury or can be idiopathic in it’s nature. Gastroparesis may be due to processes that affect the gastric enteric neurons, smooth muscle, or interstitial cells of Cajal. Frequently, gastric dysrhythmias occur in patients with gastroparesis and seems to be an underlying mechanism of decreased gastric emptying. Commonly, the causes of these gastric neuromuscular disorders are unknown. Among substances known to induce significant inhibition of the gastric motility are hormones\: glucagon and vasopressin. Recent investigations proved the crucial role of vasopressin in motion sickness seizures. High vasopressin serum level correlates with during motion sickness and vasopressin has been reported as a mediator of tachygastria. The aim of this study was to evaluate mechanism of vasopressin induced gastroparesis. Gastric motility was measured by mean of balloon introduced to stomach via previously implanted stainless\-steel fistula groups of rats\: control group, pre\-treated with L\-NNA, indometacine, sympathectomized an"]

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