Search for: [Abstract = "Fontan procedure and the influence of the perioperative factors on the coagulation status of the blood. A consecutive series of 81 children with single ventricle who were qualified for the staged Fontan palliation \(hemi\-Fontan or Fontan operation\) in a single institution were enrolled to a study. Blood samples were obtained from patients before the surgery in the operating room, 24 hours after the surgery and on the fifth postoperative day. For the assessment of liver function, serum concentration of total protein, albumin, total bilirubin, aspartate aminotransferase and alanine aminotransferase were measured. For the evaluation of coagulation profile, the concentration of fibrinogen and activity of prothrombin, factor VII, factor VIII, antithrombin III and INR were measured. The perioperative data were derived from cardiac catheterization, postoperative echocardiographic examination and medical records. In the postoperative period there was transitional increase in activity of aspartate and alanine aminotransferase and concentration of bilirubin both after the hemi\-Fontan and Fontan procedure. The elevated activity of both aminotransferases on the fifth postoperative day was observed only in the Fontan group. There was a significant influence of the atrioventricular valve regurgitation on the activity of aspartate aminotransferase, alanine aminotransferase and bilirubin concen"]

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