Search for: [Abstract = "Contrast\-induced nephropathy \(CIN\) is a serious complication after exposure to iodinated contrast media. Recent studies show that N\-acetylcysteine may play a significant role in prevention of CIN. The aim of his study was to evaluate the incidence of contrast\-induced nephropathy in patients undergoing angiography and\/or angioplasty procedures, to asses the efficacy of intravenous N\-acetylcysteine in prevention of this complication and to asses the long term adverse effects of contrast\-induced nephropathy. Results\: Contrast\-induced nephropathy was observed in 18,4% patients undergoing angiography and\/or angioplasty procedures. The incidence of CIN was significantly reduced in patients receiving intravenous N\-acetylcysteine as compared to patients receiving hydration with normal saline alone. The search for independent risk factors of contrast\-induced nephropathy was performed. This revealed the following predictors\: diabetes mellitus and impaired renal function \(with eGFR < 60 ml\/min\/1,72m²\), heart failure and volume of contrast medium administered. The risk of CIN was reduced in patients administered isoosmolal contrast medium. Probability of survival free of the following adverse events \: cardiovascular death, heart infarct, dialysis, rehospitalization due to cardiac or renal causes was reduced in patients with contrast\-induced nephropathy. Conclusions\: The rate of long\-term adverse events was higher in patients with contrast\-induced nephropathy. Administration of intravenous N\-acetylcysteine reduces the risk of CIN."]

Number of results: 0