Search for: [Abstract = "Cellular fibronectin \(cFn\) is a glycoprotein released in the event of endothelium damage. It may be involved in the regulation of vascular remodeling response. In addition, available evidence indicates its prothrombotic potential in vivo. Moreover, cFn may also participate in airway remodeling. Therefore, we hypothesized that cFn might be associated with the prothrombotic state in stable asthma \(article I\). Plasma lipoprotein\-associated phospholipase A2 \(Lp\-PLA2\) is involved in the pathophysiology of atherosclerosis. One of the Lp\-PLA2 functions is degrading plateletactivating factor \(PAF\), a prothrombotic and proinflammatory mediator entangled in asthma pathology. In addition, Lp\-PLA2 has also an antioxidant role. We hypothesized that Lp\-PLA2 might be associated with prothrombotic blood alterations in asthma \(article II\). 2 Citrullinated histone 3 \(H3cit\) is a specific marker of neutrophil extracellular traps \(NETs\) formation. There is extensive evidence that NETs are involved in prothrombotic mechanisms. In asthma, extracellular traps \(ETs\) may also contribute to persistent airway inflammation. Therefore, we adopted the hypothesis that serum H3cit may be increased in stable asthma \(article III\). MATERIALS AND METHODS\: We performed an observational, cross\-sectional study at the Department of Allergy and Immunology and the Department of Pulmonology, Jagielloni"]

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