Search for: [Abstract = "Background\: Psoriasis is one of the most common skin diseases occurring in about 0.6\-4.8% of the adult population in the world . The core feature of the disease is increased number of mitotic figures in the basal lamina of the epidermis and accelerated abnormal maturation of keratinocytes, coexistent with inflammatory cell infiltrates containing lymphocytes, monocytes and granulocytes in the dermis – which actively penetrate the epidermis. Enhanced localized inflammatory reaction may be a reflection of the systemic effect through release of various inflammation mediators such as proinflammatory cytokines. Based upon epidemiological studies some investigators demonstrate that psoriatic patients are significantly more frequently affected by cardiovascular disease. Psoriasis is most frequently associated with arterial hypertension, heart valve disease and atherosclerosis. The reasons for this relationship may be the inflammatory character of psoriasis and abnormal microcirculation on the one hand, and concomitant endocrine disorders, type 2 diabetes and oxidative stress on the other hand. Aim\: To evaluate cardiovascular disorders in psoriatic patients. To define a correlation between the clinical manifestations of psoriasis \(clinical type of psoriasis, severity of skin lesions, duration of the disease and recent eruption, frequency and reason of exacerbation\), serum levels of some"]

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