Search for: [Abstract = "Among the oldest children \(>15 years\), the MX type reaction was found in 4\/22 \(18.2%\) of Group 1 patients and in 4\/27 \(14.8%\) of Group 2 subjects, while the VD type was observed in 7\/22 \(32%\) of Group 1 patients and 3\/27 \(11.1%\) of Group 2 children. In the controls, the MX type was demonstrated in one case only \(5.9%\). NS was noted to occur non\-significantly more often in boys \[28\/82 \(34%\)\] as compared to girls \[33\/103 \(32%\)\]. Positive TT results were noted in 19\/30 \(63%\) of Group 1 and 9\/27 \(33%\) of Group 2 boys. Correspondingly, in girls, TT \(\+\) was seen in 22\/41 \(54%\) of Group 1 and 9\/35 \(26%\) of Group 2 subjects. In the controls, TT \(\+\) was seen only in 2 girls. However, in the age group of 12\-15 years when Group 1 and 2 were combined, TT was more often positive in girls as compared to boys \[Group 1\: 11\/17\(65%\) F vs. 9\/16 \(56%\) M, Group 2\: 7\/15 \(47%\) F vs. 2\/11 \(13%\) M\]. HRV analysis\: While comparing the mean values of HRV analysis parameters in children from Groups 1, 2 and 3, no significant differences were noted between the values of SDNN, SDNNI, SDANN and RMSSD in normal children and the two patient groups. On the other hand, Group 1 and 2 demonstrated a significant decrease of pNN50 as compared to healthy subjects of Group 3 \(Group 1 \- 22.7 vs. 24.5 %, p<0.003and Group 2 \- 22.1 vs. 24.5 %, p<0.002 \), depressed HF values \(Group 1 \- 3040.8 vs. 3373.1 ms2, p<0.003 and Group 2 \- 2764.5 vs. 3373.1 ms2, p<0.002\) and an increased LF\/HF ratio \(Group 1 \- 1.7 vs. 1.3 and Group 2 \- 2.1 vs. 1.3\). The author also compared the mean values of HRV parameters in children with NS and TT\(\+\), with NS and TT\(\-\) and in Group 3 children. The values of pNN50 showed no significant differences in children with NS and TT\(\-\) as compared to normal children \(23.0 vs. 24.5%, p=0.13\), but they were significantly different in children with NS and TT\(\+\) and in healthy children \(22.5 vs. 24.5%, p<0.003\). Although regardless of the TT result, the value of HF in children with NS was lower than the corresponding value in normal children, yet it did not reach the level of statistical significance. The LF\/HF ratio in children with NS was statistically higher in children with NS as compared to normal Group 3 children \[TT\(\-\) 1.47 vs.1.3, p<0.003 and TT\(\+\) 1.39 vs.1.3, p<0.05\]. A similar comparison was carried out between HRV parameters in Group 2 children taking into consideration their TT results and the corresponding values in Group 3 subjects. With the exception of pNN50, also RMSSD was significantly lower in children with MVP irrespectively of their TT results when compared to the healthy subjects \[RMSSD\: TT\(\-\) \- 59.8 vs. 67.0 ms, p<0.002 and TT\(\+\) \- 54.6 vs. 67.0 ms, p<0.001\; pNN50\: TT\(\-\) \- 23.3 vs. 24.5%, p<0.003 and 19.3 vs. 24.5%, p<0.002 \). The HF power was significantly lower in children with MVP, irrespectively of their TT results, as compared to normal children \[TT\(\-\) \- 2872.7 vs. 3373.1 ms2, p<0.003 and TT\(\+\) \- 2500.0 vs. 3373.1 ms2, p<0.001\]. The LF\/HF ratio was significantly higher in children with MVP, regardless of their TT results, as compared to healthy children \[TT\(\-\) \- 2.0 vs. 1.3, p<0.004 and TT\(\+\) \- 1.62 vs.1.3, p<0.002 \]. The complex origin of LF may cause the parameter to behave differently in children with NS \(showing a decrease\: 4329.6 vs. 4367.3 ms2\) as compared to children with MVP \(demonstrating an increase\: 4512.9 vs. 4367.3 ms2\). However, in view of the pronounced drop in the HF value in the two compared groups, the LF\/HF ratio increased. Changes observed in the 24\-hour analysis of HRV, i.e. an increase in the LF\/HF ratio and a decrease in the pNN50 and HF values in children with NS and with MVP as compared to the controls support the thesis on disturbed sympathetic\-parasympathetic balance in Group 1 and 2 children, with predominance of the sympathetic system. Under favorable conditions, the excessive adrenergic predominance may trigger the Bezold\-Jarisch reflex and cause syncope."]

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