Search for: [Abstract = "AI\- 1 \(28.44 \[ng\/ml\] vs 19.32\; p=0.02\), fibrinogen \(3.85 \[g\/l\] vs 3.30\; p=0.02\) and TAFIa \(81.23 \[pmol\/l\] vs 50.19\; p=0.02\) were found. Strong positive correlations in the OSA group were observed between PAI\-1 and both IL\-1ß \(R=0.76, p<0.0001\) and IL\-10 \(R=0.76, p<0.0001\). The two latter parameters were also correlated \(R=0.8, p<0.0001\). Similarly the significant correlations were found between CRP and both TAT \(R=\-0.4\; p=0.04\) and IL\-6 \(R=0.44\; p=0.02\). The use of oral appliances in the moderate OSA group caused a significant improvement in the polisomnographic features. A clinically important reduction in the apnea\-hypopnea index from 25 per hour of sleep to 13.1 after 3 months \(p=0.001\) and to 7 after the following 3 months \(p=0.02\) was observed. The desaturation index gradually decreased from 21.5 to 14.3 after 3 months \(versus baseline, p=0.003\) and then to 8.1 after 6 months \(p<0.0001\). The time of oxygen saturation lower than 90% and 85% gradually decreased to 5.4 min \(p<0.0001\) and 0.3 min \(p=0.03\) after 6 months, respectively. The decrease of all markers elevated at baseline was found except fibrinogen levels., In the control group no changes of all parameters studied were observed after 6 months. In the OSA group the decrease of IL\-1 ß concentrations after the first 3 months from 0.35 pg\/ml to 0.19 pg\/ml \(p<0.001\) was noted. In the following 3 months this parameter di"]

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