Filters

Search for: [Abstract = "1 \(SUCNR1\) using RT\-PCR. Results Patients with active IBD had lower fecal levels of butyric, acetic, valeric, and isovaleric acids but higher levels of lactic acid, as compared with the control group. Moreover, patients with active IBD had lower median levels of butyric acid, as compared with patients with inactive IBD \(54.7 μg\/g vs 334 μg\/g\; p < 0.05\). There were no significant differences in SCFA levels between patients with UC and those with CD, irrespective of disease activity, and the control group. Hemoglobin levels were positively correlated with acetic and butyric acid levels \(R = 0.266 and R = 0.346, respectively\; p < 0.05\). CRP levels were positively correlated with lactic acid levels \(R = 0.534\; p < 0.05\) and inversely correlated with butyric acid levels \(R = −0.573\; p < 0.05\). Patients with active IBD had higher serum TNF\-α levels than controls \(6.64 pg\/ml vs 2.05 pg\/ml, p < 0.05\). There was no correlation between the SCFA profile and cytokine levels \(TNF\-α, IL\-6, IL\-10, IL\-17, and IL\-22\). The mRNA expression for iNOS and PPAR\-γ was higher in patients with active IBD than in those with inactive IBD \(p < 0.05\). Moreover, the mRNA expression for claudin\-2 and ZO\-1 was lower in patients with active IBD than in those with inactive IBD \(p < 0.05 for both comparisons\). The mRNA expression for HIF\-1α and IL\-6 was higher in patients with active and inactive IBD, as co"]

Number of results: 1

items per page

This page uses 'cookies'. More information