Search for: [Abstract = "1\) out of 6 lysine residues, known to be important for mediating the interaction with plasmin. Glycation and acetylation overlapped at 9 sites. Incubation of α2\-antiplasmin with glucose and acetylsalicylic acid was associated with the decreased acetylation at all these sites when compared with incubation with only acetylsalicylic acid. At lysine residues 182 and 448, decreased acetylation was associated with increased glycation intensity suggesting the possible competition between glycation and acetylation processes in relation to these two modification sites. In summary, novel identified factors that affected fibrin clot properties and lysis involved\: increased protein oxidation, enhanced generation of neutrophil extracellular traps and larger incorporation of α2\-antiplasmin into the clot. The post\-translational modifications of fibrinogen and α2 antiplasmin were identified."]

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