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Search for: [Abstract = "sing FastQC software. The raw counts were normalized for library size and represented as counts per million \(CPM\) with miRDeep2 software. For multidimensional scaling \(MDS\) miRNA read count normalized for library size have been used. Statistical and exploratory analysis of miRNOME data was performed in R, limma package . The same volume of plasma from each patients for miRNA isolation had been taken. For the analysis of miRNA expression t\-test was applied as appropriate. Results In the first paper, including 110 consequtive patients operateted on because of SFN of thyroid, there were no significant differences between age \(53,1 vs. 55,4years, p=0,42\), gender \(16,6% vs. 13,1%, p=0,31\), tumour diameter \(14,5 mm vs. 19,4 mm, p=0,15\), aggregate amount of clinical and ultrasonografic factors \(1,4 vs. 1,29, p=0,71\), presence of Hashimoto disease \(33,3% vs. 31,5%, p=0,55\) and fine needle aspiration biopsy result suspicious for Hurthle cell neoplasm \(55,6%% vs. 45,7%, p=0,075\) in both groups. The second study, performed on 80 patients, revealed 129 lymph nodes dissected \(mean 1.6 lymph node per 1 patient\), all lymph nodes were clear of cancer cells. In 26 patients there were no lymph nodes in postoperative preparation. In group of patients with WDTC lymph nodes were detected more often \( 90% vs 64%, p=0,1\) and mean amount of lymph nodes was greater \(2,2 vs 1,5, p=0,13\)"]

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