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Search for: [Abstract = "relationship was shown between blood pressure values and Ucn2 in the group of healthy volunteers. An analogous relationship between logUcn2 and nocturnal diastolic blood pressure was confirmed in multivariate regression analysis with gender and age in the whole group. Furthermore, there was no association of logUcn2 with the presence of obesity, metabolic syndrome, or insulin resistance. However, a negative relationship was observed between logUcn2 and total and LDL cholesterol in the healthy group\; a similar relationship was not found in the hypertensive group. The relationship between logUcn2 and total cholesterol persisted when age, sex, and the presence of hypertension were included in the analysis. Despite differences in blood pressure values, the groups did not differ in pulse wave velocity \(hypertensive patients versus healthy volunteers\: 9.6 \[8.6\-10.3\] m\/s versus 8.75 \[7.9 \- 10.5\]ms\; p=0.167\) or the level of inflammatory factors such as\: TNFα, INFγ, IL\-1β, IL\-2, IL\-4, IL\-5, IL\-6, IL\-7, IL\-8, IL\-8, IL\-10, IL\-12, IL\-13, IL\-15, IL\-17A, IL\-21, IL\-23, hs\-CRP, MIP\-1α, MIP\-1β, MIP\-3α, GM\-CSF, fractalkine, ITAC. There was a correlation between IL\-5, IL\-8, hs\-CRP, and ITAC levels and blood pressure values, but after adjusting for age, sex and BMI the association were no longer statistically significant. Two factors were created\: Factor 1\- pro\-inflammatory \(containing IL\-1β,"]

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Dzieża-Grudnik, Anna

2024
Praca doktorska

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