Search for: [Abstract = "inflammatory drugs. Research objectives The aim of this study, was to verify whether young patients with RA and axSpA strictly controlled for not having classical cardiovascular risk factors with relatively short duration of disease, effective treatment and mostly moderate disease activity, would show endothelial dysfunction and to answer the question what are the factors contributing to their potential occurrence, with a focus on clinical, laboratory and therapeutic data. Methods This was a case\-control study conducted in 129 young \(18\-50 years old\) patients with inflammatory arthropathies \(64 with RA, 65 with axSpA\) without classical cardiovascular risk factors \(hypertension, diabetes, hyperlipidemia, smoking, obesity, family history of cardiovascular diseases\) treated according to the international recommendations and 60 age and sex\-matched healthy controls adjusted for treatment confounders \(nonsteroidal anti\-inflammatory drugs and glucocorticoids\). Patients with RA and axSpA were treated according to international recommendations and routinely monitored in the outpatient clinic. We obtained a complete set of clinical data and laboratory tests. Macrovascular endothelial function was evaluated in brachial artery by Flow Mediated Dilation \(FMD\), while microvascular endothelial function was assessed with Peripheral Arterial Tonometry \(PAT, Endo\-PAT®, expressed as Reactive"]
