Search for: [Abstract = "h respect to 5\-HT6R was \(RS\)\-4\-\[1\-\(2,5\-difluorophenoxy\)propyl\]\-6\-\(4\-methylpiperazin\-1\-yl\)\-1,3,5\-triazin\-2\-amine \(3.8, Ki = 5 nM\). In vivo studies conducted for the three most active compounds 1.2, 1.4 and 3.8, confirmed their procognitive effects. It is also worth noting that these compounds were characterized by high metabolic stability and favourable druglike properties. The results obtained in the present study confirmed the high potential of 1,3,5\-triazine derivatives as potent and selective ligands towards the 5\-HT6 receptor. The multidisciplinary research carried out was described in three publications published in international journals \(JCR, total IF>19\), constituting the doctoral thesis, and outlined further research directions in this chemical group."]

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