Search for: [Abstract = "ficiency of fibrinolysis. In article 3, the associations of lipids, their protein components \(apolipoproteins\) and their oxidation on the phenotype of fibrin clots were analyzed. Oxidized low\-density lipoproteins \(Ox\-LDL\) as well as apolipoproteins have been shown to be stronger predictors of prolonged clot lysis time in comparison with serum lipoproteins. Additionally, patients who use statins had shorter lysis times and lower serum Ox\-LDL, suggesting a positive effect of lipid\-lowering agents on oxidative stress and fibrinolysis in patients with severe AS. Additionally, increased Lp \(a\) level has been associated with decreased fibrinolytic capacity. Given the use of different assays for measuring fibrinolytic capacity in various disease states, it is possible to choose the assay most appropriate for the particular clinical setting. Moreover, chose at least two different assays could provide better characteristics of fibrinolytic capacity in a specific patient group. In AS patients global higher oxidation stress contribute to more impaired fibrinolysis, altered fibrin clot structure, and ultimately to the progression of AS. Moreover, dyslipidemia along with increased amounts of apolipoproteins, Ox\-LDL, and Lp \(a\) contribute to prothrombotic fibrin clot properties, in particular impaired global fibrinolysis in AS patients."]

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