Szukana fraza: [Abstrakt = "e study and control group was determined using immunohistochemical methods. In addition, severity of skin lesions was also assessed using the CLASI scale in the study group, before the initiation of systemic immunomodulating and immunosuppressive therapy and after the 3\-6\-month treatment period. The analysis of correlation between the expression level of type 7, 8, 9 Toll\-like receptors and the response to hydroxychloroquine treatment, measured by a percentage decrease in the CLASI index after 3\-6 months of treatment, was performed. Correlation between severity of the disease, measured with the CLASI index before the initiation of systemic immunomodulating and immunosuppressive treatment, and selected parameters in the study group were also evaluated. Results\: Patients with a higher CLASI index significantly more often presented symptoms in the form of\: arthralgia in the hands and feet and\/or knees and\/or elbows, lymphopenia and anemia of chronic diseases. A relationship between the disease severity index assessed on the CLASI scale and the presence of thrombocytopenia in patients with CLE was at the border of statistical significance. There was no evidence of type 7 TLR expression in the epidermis in patients with CLE and in the control group. Skin biopsies of both healthy skin and CLE lesions were characterized by expression of type 8 and 9 TLRs in the epidermis, epithelial"]

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