Search for: [Abstract = "cemia adversely affects processes related to AS progression by enhanced in loco activation of the NF\-κB pathway. Our study suggests that maintaining HbA1c and fructosamine within the reference range in patients with AS and concomitant DMT2 may retard the rate of AS progression. Patients with severe AS exhibit hypofibrinolysis. High levels of serum Lp\(a\) are associated with elevated levels of OxPL, and better than Lp\(a\) predict hypofibrinolysis. Additionally, the overexpression of PAI\-1 within stenotic valves, caused by lipid accumulation, is mediated by enhanced activation of the NF\-κB pathway and, at least in part, contributes to hypofibrinolysis. Therefore, our results suggest that the NF\-κB pathway may be a potential therapeutic target in AS."]

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