Search for: [Abstract = "The subject of this dissertation research is the evaluation of the influence of various oxidising compounds on the oxidation process of selected fluoroquinolones \(FQs\). Stability is one of the key requirements that should be met for both medicinal substances and drug forms. Changes in the structure of a chemical compound that 1s a component of a pharmaceutical preparation can lead to a reduction in its therapeutic efficacy and changes in its physicochemical properties, or even to the formation of products with harmful or toxic effects. Among the chemical reactions that can accompany processes associated with drug transformations are oxidation. \(Oxidation is one of the chemical reactions that can accompany processes associated with drug transformations.\) One of the tools used to assess stability, identify products and degradation pathways for pharmacologically active substances as well as pharmaceutical preparations are stress tests. In the present study, it was decided to investigate the oxidation of FQs under stress conditions in the presence of selected oxidising compounds, i.e. hydrogen peroxide, potassium manganate \(VII\) and 4,4'azobis\( 4\-cyanopentanoic acid\). The project planned several main areas of research to assess the oxidation of selected FQs. The first involved the development and validation of methods for the determination of the compounds"]

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