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Search for: [Abstract = "Introduction Hypertension is one of the most common diseases in the world. Among the established classic factors involved in the development of primary hypertension are the excessive activity of the renin\-angiotensin\-aldosterone system and the sympathetic nervous system. The involvement of the immune system in the development of hypertension and its complications is also increasingly emphasized. Despite abundant evidence in preclinical studies of the effects of inflammation on vascular endothelium and blood pressure values, there is a lack of work evaluating the association of inflammatory interleukins with blood pressure values in both chronic inflammatory diseases and hypertension itself. In addition to inflammatory interleukins, new factors such as urocortin 2 may also influence the development of hypertension and the regulation of blood pressure values. Aims of the study The purpose of this study was to evaluate the relationship between markers and blood pressure values, and to determine the relationship between inflammation and hypertension and vascular stiffness in chronic inflammatory diseases using rheumatoid arthritis and ankylosing spondylitis as examples. In addition, we also wanted to determine the relationship between blood pressure values and levels of Ucn2, a peptide with postulated vasodilatory effects. Materials and Methods\: A total of 177 patients were st"]

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Dzieża-Grudnik, Anna

2024
Praca doktorska

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