Search for: [Abstract = "Hyperemia Index \[RHI\]\) and Flow\-Mediated Skin Fluorescence \(FMSF\). Multiple parameters were used to comprehensively quantify functional endothelial responses in FMD, PAT, and FMSF. Results The mean \(SD\) age of the patients was 35 \(9\) years, the mean duration of the disease was 6.97 \(6.37\) years and average disease activity was moderate or low\: DAS28\-ESR 3.53 \(1.5\), DAS28\-CRP 3.3 \(3.2\), BASDAI 3.5 \(2.1\), ASDAS 1.98 \(0.96\). FMD \[%\], RHI, or HR index were neither altered in patients with RA and axSpA compared to the healthy control group. Other parameters characterizing FMD, PAT or FMSF \(e.g., Time to FMD Peak, Shear Stress, Shear Rate, Hypoxia Sensitivity, Power Spectral Density Ratio\) were also not changed. However, in 54 patients with inflammatory arthropathies \(RA and axSpA\) who had endothelial dysfunction of conduit arteries \(FMD < 7%\), higher total cholesterol \(TC\) levels were detected, 4.86 \(0.79\) mmol\/l, and higher low\-density lipoprotein \(LDL\) concentration, 2.85 \(0.79\) mmol\/L. On the contrary, the subgroup with higher C\-reactive protein \(CRP >2 mg\/L\) had higher FMD \[%\] than the subgroup with a cut\-off value of CRP lower than 2 mg\/L \(FMD 9.52 \(\(4.25\)\) vs 7.64 \(\(4.63\)\), p=0.03\). In contrast to FMD, neither PAT \(RHI\) nor FMSF \(HR index\) discriminated patients with higher and lower cholesterol or CRP. Interestingly, the HR index was lower in a subset of patients with axSpA"]
