Search for: [Abstract = "Background\: Electroconvulsive therapy \(ECT\) is the most effective treatment in a variety of psychiatric syndromes \(especially mood disorders\). However, one of its adverse effects is neurocognitive dysfunction. Declarative memory impairment after ECT is unquestionable and well investigated. There are only few ambiguous studies focused on nondeclarative or working memory changes during ECT. OBJECTIVES\: The main objective of the presented study was to investigate working memory changes after ECT in comparison to pharmacological treatments. METHOD AND CHARACTERISTING OF THE STUDY GROUPS\: Working memory functioning was assessed in 32 unmedicated patients with major depressive disorder \(DSM\-IV\) who were then administered bilateral electroconvulsive therapy \(ECT\). Two additional groups were organized for comparision\: first treated with Tricyclic antidepressants \(TCAs \; imipramine or desipramine 150\-250 mg\/day\; n=29\) and second treated with newest antidepressants \(venlafaxin\; mirtazapine\; reboxetine, n=30\). Hamilton Depression Rating Scale \(HDRS\) and Beck's Depression Inventory \(BDI\) were used to assess the efficacy of antidepressant therapy. Cognitive functions were assessed with neuropsychological tests\: Stroop A and B, TMT \(Trial Making\) A and B. The patients' status was evaluated 1 day before the treatment and 1 day, 2 weeks, 1 month and 6 months after the first ECT procedure. RESU"]

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