Search for: [Abstract = "Acute coronary syndromes are the result of acute imbalance between myocardial demand for oxygen and the possibility of delivery by the coronary arteries. This condition is usually caused by a resulting massive thrombus that develops in place of a ruptured atherosclerotic plaque, leading to partial or complete occlusion of the coronary artery supplying a miocardium. An occlusion or severe stenosis \(angiographic culprit lesion\) of the infarct related artery \(IRA\), in STelevation myocardial infarction \(STEMI\) as well as in non\-ST\-elevation myocardial infarction \(NSTEMI\), is frequently located at the site of the maximum thrombus burden, whereas the origin of the plaque rupture \(the true culprit\) can be situated proximal or distal to it. This may lead to incomplete stent coverage of lesion which is responsible for acute coronary syndrome, if the procedure was performed only under angiographic guidance. We examined coverage of the true culprit lesion in 20 STEMI and 20 NSTEMI patients who had TIMI 3 flow restored in IRA \(with or without thrombus aspiration\) with angiographically\-guided direct stenting. The lesion was imaged with virtual histology intravascular ultrasound \(VH\-IVUS\) pre\- and postintervention \(blinded to the operator\). To assess the phenomenon of \"geographic miss\" \(GM\) in relation to the previous implanted stent, a composition of plaque by virtual histology was performe"]
